Medical Information

In this section, you will find detailed information on coagulation basics, most common medical conditions requiring long term oral anticoagulant therapy and the benefits of Coagulation Self-Testing for you and for your patient.

Our experience in Coagulation Monitoring dating back to 1993 can help you get a clearer overview about our CoaguChek product line. Please make sure to contact your local Roche Diagnostics representative for any further questions.

Basics of Coagulation
Blood coagulation plays a crucial role in haemostasis though it only occurs through the interaction of numerous factors. The human body, through a complex mechanism that causes blood to clot if a wound occurs, protects itself from excessive blood loss on one hand, and from excessive clotting on the other hand. more

Oral Anticoagulation
It is vital that the haemostatic and anti-haemostatic mechanisms are fully functional and in balance. Even a slight change in certain coagulation factors or inhibitors can lead to excessive blood coagulation and thus to thromboembolism. more

Prothrombin Time/International Normalised Ratio
Prothrombin time and International Normalised Ratio are the parameters used to follow up the success of oral anticoagulation therapy. Here you will find a short explanation of the different terms used in the field of anticoagulation monitoring. more

Indications for PT/INR Monitoring
The main indications for a patient to receive vitamin K antagonists (coumarin derivatives) and to monitor PT/INR values are the following: more

Benefits of Coagulation Self-Monitoring
The CoaguChek family of instruments helps both you and your patient to benefit from Coagulation Self-Testing. An increase in time within the therapeutic range produces a decrease in major potential complication rates. more